Re isolation. From high-assurance security, I believe the first, secure kernel that was general-purpose was this one:
http://csrc.nist.gov/publications/history/schi75.pdf
Types. Guess that would be ALGOL.
LLVM. BCPL seems to have gotten the idea started with a two-pass compiler that went from complicated stuff to byte-code (O-code) then to assembly. That got ported to PDP-11 in form of B & then C. Wirth further developed it & popularized it with P-code in Pascal/P. Helped non-compiler experts port it to 70 architecture in 2 years whereas compiler experts could target something easy. Did it at hardware level with Modula-2 & M-code assembly. So, either Richards of BCPL or Wirth of P-code get credit for such a concept. Maybe both.
re packaging. I got nothing. Anyone know what the first package managers were that had something inspiring modern functionality? Those ahead of their time.