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Small/Medium Business. SME is the more usual abbreviation, here in the UK at least (Small/Medium Enterprise).

Small and midsize businesses

"midsize enterprise is defined as organizations that make more than $50 million, but less than $1 billion in annual revenue"

So -- no -- businesses with $1 billion in revenue are not running off a Facebook page.

SMB = Small or Medium-sized Business

Small/Medium businesses I believe.

Small and Medium Business(es)