Could always run in a 3M respirator. The reduced airflow would make it extra intense, if not untenable. On the other hand, frequent breaks due to being stopped by police would probably balance that out.
Then again, hauling your own air supply would result in far easier breathing and better cardio due to the added weight.
Runnning with it, however, is a whole different animal.
My dad has idiopathic pulmonary fibrosis or IPF it's probably from breathing in small particles over the years which causes scarring of lung tissue. Although the idiopathic part means how it occurs is not known for sure. He worked a blue collar job and often breathed in dust from various things.
Lungs are only for air don't mess with your lungs!
There is also this inhaler containing ectoine, but this wouldn't protect against particles entering the brain via olfactory nerve:
"An inhaler that protects the lungs against air pollution has been developed by scientists and could help the many millions of people affected by toxic air to avoid its worst effects."
https://www.theguardian.com/environment/2016/sep/16/new-inha...