For a simple site, it's probably not that big of a deal to hook in jQuery and write some basic scripts.
In my limited experience, if you are writing a Single Page Application, it gets really hard to rationalize changes when everything is hooked in through the DOM. It also gets pretty expensive with mobile browsers as DOM elements carry a huge list of properties and attributes; this why I think libraries like React were made as to have data change and manage state as opposed to the DOM.
At the end of the day, the end user and businesses don't care about what technologies that you use, they just want a site that works and can be delivered on time. I just think that with jQuery, there is a lot of cost in terms of making complex changes in the view that other libraries such as React/Angular/Mithril have been designed to get around. These libraries, however, do have a cost in terms of complexity that I think jQuery never really had.