The real problem is that current economy doesn't let those ideas grow.
This has always been true.
Therefore any kind of work aimed at making peak mental performance better would be the most important, to start cascade of improvement and fuel it.
I think that making people constantly scramble to meet the next deadline puts a harmful damper on innovation and Big New Ideas. https://www.theguardian.com/science/2013/dec/06/peter-higgs-...
We also may need to spend more effort explicitly targeting our R&D industry towards finding mysteries and solving them. Basic scientific advancement, after all, comes precisely from exploring the unknown rather than from merely innovating within the bounds of the already-known.
And then there's patent reform and such to think about. Blah blah.
But you should take everything I say with a grain of salt, since I work for an R&D company.