Most bio-peeps and medical personnel have an understanding that there is a difference between .png, .jpg, and .tif. But the diff of .tif and .tiff? No idea, let alone the +/- of a .png to a .jpg. It's all just a picture to them.
So, trying to tell them that you can losslessly convert them, though maybe true, is not a good idea. .tiff can handle a stack of images and you only have to call it once in a MatLab script, .jpg cannot and will result in a shitfit as they try to load in an entire folder of images. Then you get into bit-depth and God help you if the conversation ever has you trying to pronounce 'int', 'float', 'str', or 'double'. The class of a variable? Dude, this person could care less and will get out a protractor and measure tail flicks off a print-out before any of that will ever sink in.