How about placing in our blood flow a CRISPR that embeds into mosquitoes' DNA something that makes all their offspring sterile after four generations? For three generations they should be fertile thus moving genes around.
http://www.oxitec.com/our-solution/technology/the-science/
http://www.straitstimes.com/world/americas/brazil-to-use-fac...
It doesn't use CRISPR or have the amazing generational sterility though.