I also know someone from college who had some sort of thyroid condition, and she slept very little and was very skinny. She was also awake and hyper so much, she sewed all of her own clothes. (Yes, that's just like the girl in Real Genius!)

However, I also lost 10 pounds recently by doing just two things: sleeping 7 hours a night instead of 4 or 5 and cooking my own meals instead of eating out.