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The happy hacking keyboard has both the esc and ctrl keys in these (proper) positions. Highly recommended for vimming.

Yeah, but re-mapping is easy. Personally, I'm fond of the (gasp!) Microsoft 4000 Natural Keyboard, with several remappings.

A-men. Plus, OS X makes swapping caps<->ctrl super easy, so do that on a MS4000 and you're two large steps nearer to healthier longer-lasting wrists.