"The Midwest and Ohio in particular has always had three things going for it in terms of business climate: a cheap, close supply of energy, access to transportation, and a highly trained work force."
And yet the technologically inclined flee for the coasts, where life is expensive. The next Silicon Valley isn't going to be in Nevada, Arizona, Ohio, Kansas; it's probably not going to be in Illinois. It's going to be somewhere with high amenity value to highly productive technical people; i.e., a big international city.