Is there a reason for the odd layout? Some pathalogical issue with utoplacement doing the best it can to fit components into a limited space? Trying to avoid sharp edges in the track for some weird capacitance reason? Or maybe it's deliberate to try and drive its users insane... anyone actually know?
I guess in this particular case, the (many, and sensitive to total length and relative length with respect to each other) traces connecting CPU and RAM had been routed in isolation first. These chips seem to be 45° rotates against each other.
Then the group of CPU & RAM had been rotated too leave enough space for power/camera/HDMI, I'd guess.
It looks strange, but frankly there is no real reason (besides aesthetics) to favor any particular orientation.
I can't imagine turning in a schematic drawn like that (parts rotated) for a test in college.