>You can tell a startup is focusing on the wrong thing when: They're using the 'newest', most obscure, programming language or frameworks available because it's the 'best' for some unscientific reason.

I don't think he was talking about technical details, he was merely trying to emphasis on the importance of ignoring trivial things that might not mean (at an early stage esp.,) as much as one might think... And I'd agree..

At an early stage one should have google like garage office and just stay focused... focused.

twitter isn't facing problems due to less revenue.. but due to abundance of the expenses.... just gave a very broad example to make the point.