One could argue the success of most companies in SV are based in part on indifference.

Disruption creates many losers as well as winners, not everything is a positive sum game.

Indifference towards second order impacts due to a focus on the primary goal (economy is really really bad about to explode etc) is pretty common.

I think Thiel does acknowledge some of the ugliness though looking at his speech, he's just focused on the necessity for immediate change versus status quo/gradual shifts & calls for him to be disavowed for doing so still don't ring quite true.