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Thanks for the warning. I put macOS 12 installation on hold for more superficial shortcomings. This one would have taken me a bit longer to find.

I have adopted the practise of installing new OS releases on a separate test partition first. Blindly updating the main system can be a really bad trap.

Golang broke on macOS Sierra as well - and since all Go binaries are statically linked, the practical impact is that all compiled binaries stopped working until a compiler update was released.

From the Go1.7 release notes: "Binaries built with versions of Go before 1.6.3 will not work correctly on Sierra."

I don't know what the underlying cause was.

Do you have a bug reference for this OCaml issue? It works fine here for me on OSX 10.12.

Just tried to track down the details, it looks like I was thinking of an Opam problem specifically, and the last update was about 3 weeks ago, so likely the issue is already resolved.