I love where this is going. I now use Chrome's Dev channel or a WebKit nightly for development, and only launch Firefox/Firebug to do compatibility testing.
Although I still have a ton of respect for Firefox's rendering engine, the browser just feels wrong on the Mac -- not to mention it's slow launch times. The Inspector Panel has caught up to Firebug's functionality in many areas and is now starting to surpass it.
What kills me is launching IE in a VM and discovering how archaic its developer tools are.