I recently signed up for Sync.com, due to their prioritisation of security features and they seem like a good company. I have come across some minor bugs, but I sent these onto their customer support who were reasonably responsive. Even with these minor bugs I'm still happy with the trade-off to move off Dropbox.
I must admit the most difficult part was definitely the services I used that directly integrate with Dropbox, like 1Password syncing. So I also had to find solutions to not just Dropbox, but also third-party services that integrated. For 1Password, I signed up for their Account option where they handle the syncing for you at a cost of $2.99 per month. Again, another trade-off I was happy to make.