> Why are you certain folks have tried to make a self-sustaining Antarctic colony? I don't see why anyone would bother. You can get supplies from the outside. Activity on the continent transitioned directly from exploration to scientific outposts.
Nobody said they _had_ to, but I'm sure someone has tried over the years out of a scientific interest. (Although I have no source for this, so it's unsubstantiated unless someone digs something up).
> The transit time to Mars with this system is 3-4 months
Travel time depends on trajectory, however safe estimates usually are around 6 months each way.[1]
> It's possible that the reduced gravity on Mars would continue to cause harm, but I rather doubt that it would be so bad as to make the whole venture impossible
Well, the effects we're observing now (for the first time!) are largely from Scott Kelly[2]'s year in microgravity. Going to mars and back takes around 1 year's time (6 months approximately each way), plus we assume they'll stay on the surface longer than a few hours... so these may prove to be serious complications. The scary thing is, few talk about these issues when dreaming about traveling to Mars (Musk included, apparently).
[1] http://www.universetoday.com/14841/how-long-does-it-take-to-...
[2]https://en.wikipedia.org/wiki/Scott_Kelly_(astronaut)