There are some incredibly annoying basic missing features in Chrome dev tools. Like you still can't just hover over a variable, you inexplicably need to highlight it. Functionality that IE dev toolbar had 10 years ago. And don't even get me started on their shitty black boxing solution, something that should be as easy as right clicking on the file you want to black box, but no, time for some bloody regex foo.
It's better than Firefox + IE, by it's not better than proper IDEs by a long shot. And it's got "designed by a programmer" written all over it, the UX is awful.
VS has the 'immediate window' which allows you to execute (almost) any statement within the context of the local scope, including intellisense and autocomplete.