I took Modafinil for a year after reading Gwern, 100mg twice a week on average. It relieves a lot of anxiety for me and also acted as a great appetite suppresant, but I also worry it has caused me some cognitive decline. I feel like a bit of a zombie sometimes, kind of dead emotionally, not talking as much, feeling generally dumber. Can't say for sure as I've had a lot of stress in the last few months too, but people should be very careful with these things.