If you land a position at a Big 4/5, you can expect to make 300k+ (total comp), and still retain flexible work hours, PTO, etc. Competition for dev talent is fierce, and with good interview / negotiation skills, it is possible to make integer multiples of your current comp without sacrificing perks such as a good team and flexible hours.
Also, read this: http://haseebq.com/how-not-to-bomb-your-offer-negotiation/