Sure - I've flown these kinds of batteries into the ground from great heights doing dumb stuff with drones/quadcopters/modelaircraft - and abused them pretty badly while charging. I've occasionally had Galaxy Tab 7 style "incidents", and take suitable precautions given my experience with the risks.
The 7 cell 5800mAHr batteries I use on the bike are the biggest and most dangerous ones I use - and I do treat them with respect. I charge them in the middle of the concrete floor of my garage, inside a besser block, at least 1.5m from anything valuable or flammable. I dispose of them if they go puffy (I've sent two off the the e-waste/battery-recycling in two years - one of them I knew I'd let run down way too far when using it elsewhere, down under 19V which the bike's controller wouldn't ever do (it cuts out at 22V) and it never managed a good charge again, the other I'd been quick charging occasionally (although not really fast enough to explain the shortened lifespan - I can only _just_ hit 2C charge rates with my charger, the battery _should_ be good up to 5C really...))
If you don't know (or want to learn) the risks, or if you're less risk averse (or less able to mitigate the risks due to not having suitable space to let a lipo fire burn itself out) LiFePO4 is a slightly heavier but much safer battery chemistry. I _almost_ got hold of a bunch of cells from a crashed Tesla's battery pack a while back - they'd make a nice ebike power supply. If I can get my hands of enough of them at a reasonable price, I'm planning on electrifying one of my motorcycles with 30+KW of electric power...