not sure why, but the use of the word "wrong" just bothers me. why can't a gambling addict be an experimental variation that MAY result in something game-changing (i'd bet a lot of the greatest entrepreneurs are basically risk addicted gamblers).
Regarding the former, hard work and study can affect the outcome. The latter are machine programmed and can't be beaten.
I don't know, but wouldn't be surprised if these two types of gambling attracted different types of people.
Dedication, vision, relationships and a whole host of other factors combine in successful business management, which can go a long way towards mitigating risk.
In fact, I would guess that most human activity is negative-EV.
Many actions are considered wrong and a particular brain activity is somewhat arbitrarily chosen as the single cause of that action, and thus wrong in and of itself. It's as useful as saying that phishing happens because the TCP handshake is fundamentally broken.