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A 15-second google search reveals this:

http://www.marksdailyapple.com/artificial-sweeteners-insulin...

Some interesting links to pubmed there. Seems that aspartame does not affect insulin fwiw.

Mark has a bit of an agenda. He is not nearly as full of shit as many others (to include many in academia) but he nonetheless has a financial conflict of interest due to the way he makes a living. I'm not saying he is wrong, but I am saying that you must think critically in the presence of COI.

Mark Sisson's intellectual rigor is certainly higher than the average blogspam but not as high as the best diet bloggers in the paleo or fitness communities (e.g. Stephan Guyenet, Alan Aragon). That said, his biases would tend to go against artificial sweeteners, rather than towards them. In that article he suggests that you shouldn't eat them, even though he thinks the evidence of their insulin response effects is weak at best. If your point was that you should take all of his advice with a grain of salt, I definitely agree, since he promotes many things which have at most a marginal effect.

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