I do a lot of optin email. Here are some examples of bounced emails that people use to sign up:
* somename@gmail.co
* anothername@yhoo.com
* myemail@hotmial.com
These are very common errors that occur nearly every day. A regex isn't going to help here. What does help, is a notification that asks people to verify what they typed –– if the email contains an obvious, common error, such as one listed above.