LLV8 – An experimental top-tier compiler for V8
github.com
github.com
This would especially make sense along with an "optimized cocde cache": cache pre-compiled optimized versions of JavaScript, such as common JavaScript libraries, based on hash.
That's partially because the amount of API churn for LLVM and for native Node.js bindings is high. It's actually a lot of work to keep up with LLVM in particular.