If you're doing neuroscience image analysis, you probably want to take a look at Bolt, Thunder, Lightning:
http://bolt-project.org/ http://thunder-project.org/ http://lightning-viz.org/
and associated work going on at the Freeman lab at HMMI:
http://bolt-project.org/ http://thunder-project.org/ http://lightning-viz.org/
and associated work going on at the Freeman lab at HMMI:
The Human Connectome Project's neuroimaging approach
http://www.nature.com/neuro/journal/v19/n9/full/nn.4361.html