There are so many tens (hundreds?) of thousands of people whose livelihood is tried up in arresting people for drug crimes that shouldn't be illegal in the first place. Think about all those DEA agents making $100k a year plus their pensions, all those judges and public defenders, all those private prisons full of people doing possession charges. All those local cops employed to keep an eye on them during probation.
It's absolutely disgusting and ruins peoples' lives on a daily basis, but totally expected behavior in a society that only cares about money (aka capitalism).
I am sort of surprised there isn't a lot more backlash against the DEA for this horrible move last week, but then again, the pro-pot legalization movement isn't all that impressive either. The most annoying thing about marijuana is fucking idiot stoners representing the brand.
edit: and don't even get me started on the huge amount of needless deaths in northern Mexico directly caused by the War on Drugs. Go read 2666 if you want a sliver of an idea of how bad it is there. But hey, to the average American, they are brown people so they don't care. Disgusting.