Would be funny if we eventually end up with some artificial intelligence algorithm that processes content on a webpage and modifies it for the end user to remove any content they don't want to see.
I totally expect this to happen. Although it will only lead to advertisers also using those programs to check their content and modifying it until it fits. I mean we already have pretty much an always on going evolution in advertising, why should it stop.
Readiblity bookmarklet does just that but it is very simple heuristic and is good enough for articles/layouts with single main column.