I wonder why mixing cns depressants is so common? Is it because opioids are so expensive / hard to get, and benzos/alcohol easier to get and cheaper? Or is it simply a better feeling mixing them...
Some people take them to increase the nod. Others might have insomnia and don't want to take so much opiates to really sleep.
Edit: And there's obviously some information on this, somewhere because e.g. IV opiate+midazolam is quite a common thing. [In a 3rd world pharmacy, I was actually offered liquid midazolam as a sleep aid when I complained long-lasting benzos were too long-lasting and asked for a medium-duration sleep aid.]
oh, and 4. combining a stimulant with a larger/more euphoric dose of the CNS depressants so if the respiratory stimulating effects of the stimulant run out first, respiratory depression ensues
I didn't understand why people mixed in benzos, unless to curb withdrawals.