It really depends on the project. I'd prefer Clojure or Erlang for most frontends, a Lisp for the backend of an expert system, and C++ or OCaml for any heavy lifting. Python still can be a great choice for all sorts of systems too. Swift and Rust aren't quite there yet but for a startup might be worth a look in time. We're not talking about "nobody ever got fired for choosing IBM" business here and being risk-averse is itself risky.