Leaded gasoline was a superior fuel in many respects but was clearly a fraudulent mistake (it was sold with false assurances of safety).
Even the original Luddites were not wrong in their original critiques - the technological innovations of machined industrialization did indeed replace workers and enrich employers. (That such technological innovation also created wealth was poor consolation for the workers getting the short end of the stick).
Chemical warfare was horrible enough to have military strategists more than willing to agree to ban its usage.
New is not universally a good. In fact, every change has benefits and detriments that will be unequally distributed. History has also shown a tendency for the detriments to be mostly felt by the poor and disenfranchised.
It seems fair to be cautious about the new.