Hi Marcus, have you ever taken a look at Nim? It's quite similar to Swift in several respects, but it has a primarily Python-like syntax (including indentation by blocks rather than braces) with bits of Ruby & others mixed in.

Useful links: http://nim-lang.org/ , http://nim-lang.org/docs/tut1.html , https://nim-by-example.github.io/ , http://nim-lang.org/docs/manual.html

At work, we use Python as our interpreted language & Nim as our fast, strongly-typed, compiled language. We created Nim-Pymod to enable Nim code to be compiled into Python modules: https://github.com/jboy/nim-pymod

There's also a web-framework in Nim called Jester, which describes itself as "a Sinatra-like web framework": https://github.com/dom96/jester