I know this is largely anecdotal and not very scientific, but just listen to [what trans people have to say about it][]. There are some people who do regret transitioning, but usually the reason they give is the discrimination they experience because of transitioning, not any genuine dissatisfaction with themselves.

There is [a small propaganda war being waged by transphobic conservatives][] to create the illusion of a large percentage of trans people that regret their transition, but just look at their references. You'll find every link is either to the Daily Mail or some other hate group referencing even more hate groups in a big web of circular reasoning.

Generally, there's not a lot of hard data to work with on issues relating to the trans community right now, which is a little frustrating, but hopefully there will be more soon as the scientific community is finally starting to recognize the LGBT community and conduct real science on this stuff.

[1]: https://www.reddit.com/r/asktransgender/search?q=regret&rest... [2]: http://www.sexchangeregret.com/