Can't weigh in on Mezzanine, and haven't built a site in any in over a year so things may have changed, but the big difference between Django-CMS and Wagtail come down to how your content is modeled. If you're looking to have a page with a variety of widgets that can be mixed and matched, then Django-CMS is probably more suited. If you've got a structured page where your users are going to be filling in predefined fields and the pages have more consistency then Wagtail is probably better.

The backend of Wagtail is completely geared towards authors, and a lot easier to use in my opinion, and it's got a media library built in. Django-CMS extends the standard django admin backend, may require a third party plugin for a media library, and tends to encourage more frontend editing, so authors will more immediately be able to see how a page looks. It also tends to be more flexible and can do more (which may be a good thing or a bad thing, depending on your goals). If you need more control over permissioning, workflows, etc. then django-cms may be a better choice.

I personally love both of them, and would recommend either.

I chose Mezzanine twice because community support works better than the other options (check GitHub issues and the mailing list traffic and feedback). I can't compare them technically side by side but I found easy to extend Mezzanine just looking into Django docs instead of looking at the specific Mezzanine implementation.

One point that put me in doubt in favor of Django CMS was the support for editing single page sections, you can do that in Mezzanine but it is not "native".

I may be biased =) but, I would use django CMS + Aldryn News & Blog, and perhaps Aldryn Jobs to start.

The thing that drew me to django CMS to start with still exists today, which is that django CMS recognizes that Django is a powerful application framework and the CMS embraces this. It also provides powerful front-end editing capabilities for you and your non-technical stakeholders, even for existing Django apps.

Try them all! They take different approaches, and one might suit you better than another.

django CMS has addon applications for both jobs (Aldryn Jobs) and weblogs (Aldryn News & Blog).

If you're interested, you can join a free Guided Tour each week that will actually cover some how this all works in django CMS: https://www.divio.com/en/academy/aldryn-cloud-django-cms-gui...

For a fully-blown jobs site by the way you'd probably want to expand the Jobs application but it's open source software already so could be a good start.

I'd back Wagtail. I had a look at both Mezzanine and Dj CMS a while ago and was relieved when I stumbled on Wagtail. Much flatter learning curve and the then recently introduced Streamfield was super helpful.

Doesn't hurt that it looks awesome as well.