Various versions of Windows are used on probably 90% or more of desktops and laptops, in both home and business settings. It still sees widespread server use.
Word, Excel, PowerPoint and Outlook are widely used.
SQL Server is quite common within many enterprises.
Azure is a major player, and is seeing more and more adoption.
The porting of .NET to Linux and OS X is making Microsoft's development technologies available to a wider audience.
The Xbox brand of consoles is quite popular.
Microsoft has numerous offerings, across a range of sectors, that have huge uptake and are quite successful. I don't think that "irrelevance" is the way to describe Microsoft or their products.