What's the alternative? Standing on the pedals? Or are there other styles of seat, not covered by the word "saddle"?
But my biased opinion is buy a recumbent! Fewer back, neck, and nether region issues, plus, they have comfy seats! http://www.bacchettabikes.com/recumbent-bikes/
VERY comfy seats! http://www.hpvelotechnik.com/produkte/scorpion_plus20/index_...
A long wheelbase (crank behind the front wheel) and a more upright riding position is perfect in city traffic. On my commuter, my eye level is about even with drivers in crossover vehicles.