I'm also using the Python-based Pelican for my personal blog [1]. I was originally using a homebrew solution, but decided to switch over to something a little better-tested. The Fabric deployment options [2] are really great. Of course the static nature means that a JavaScript-based comment system is needed, for which I'm loving Isso [3] - it's self-hosted, lightweight, doesn't have spam issues and respects user privacy.
[1] https://mikeanthonywild.com