"... Unless you are a high risk target, spending almost any time beating SELinux into shape on your machine is a bad tradeoff and pretty much a waste ..." -- https://utcc.utoronto.ca/~cks/space/blog/linux/SELinuxToxicM...
If you are a high risk target, SELinux is a great option.
Also, to refer to the partial disagreement, here is my exact feeling...
"I'm a security aware sysadmin and yet yesterday I casually admitted that I made less-secure choices because the really secure option was too annoying and potentially inconvenient. In fact this is not the only case where I make this tradeoff, picking a less secure but more convenient option..." -- https://utcc.utoronto.ca/~cks/space/blog/tech/SecurityNotImp...