Review my startup: Speechable.com
speechable.com
Speechable™ is a free photo service that lets you easily upload and add speech bubbles to your photos and share them with friends via email or on Facebook®, MySpace®, Orkut, blogs, and message boards.
speechable.com
1) Instead of squeezing your content between two vertical ad banners, move all your advertising to the right side, and put your content on the left. Putting all of your content between two giant banners gives me the impression that you don't care about your content, and you're more interested in pushing your ads.
2) I would probably ditch the Comic Sans for a cleaner looking font, but that's just me.
3) I would move your content higher 'above the fold', and clearly delineate when it starts. For example, the current top image is 'Message from Jellied Awful'. It looks a bit weird cause of all the extra whitespace in the image itself, and I can't tell if it is supposed to the part of the page, or if it is user submitted content. Putting a border around it might help.