A while back I had to teach myself Fisher matrices and the Cramér–Rao bound to solve a problem I was working on. I quickly found that 90% of statistics textbooks and lecture notes on this subject are completely useless for people like me who want to arrive at a number, not some abstract expression involving angle brackets or measures or E[...] or whatever.
The Wikipedia article on Fisher information [0] is one such example of a resource that is full of useless formal crap that crowds out an explanation for real people about how to use this statistical tool. This book appears to be of the same ilk. (Also, this book apparently does not discuss the Cramér–Rao bound. Ironic given the book's title.)
If anyone is curious, the single best explanation of the Fisher matrix and the Cramér–Rao bound that I have found is tucked away in an appendix of the Report of the Dark Energy Task Force [1]. In one page they manage to concisely and clearly explain where the Fisher matrix comes from, how to compute it, and how to apply the Cramér–Rao bound.