Here is the thing I just dont get. Why doesnt some tech savvy organization create a white label solution that companies can either slap a subdomain on and invite "Customers" to fill ad supply. Self host the curated assets through said white label solution. Moderate with sophisticated computers that are not subject to the vast majority of mal ware (excluding 0-day obviously), and move on. Im sure someone could easily serve the ads off of the main domain anyway to circumvent all of the ad blockers on subdomains.
This is a perspective from the outside looking in, but people seem to just complain about the problem instead of looking for solutions.
EDIT: BAH, so there is a conversation from last year. https://news.ycombinator.com/item?id=10221859