1. Even more distributed crawlers than before. You used to need to at least know how to cycle through IPs or get a botnet up and running, now either the domain bans the entire subnet or it does other shitty things like putting up captchas. 2. People thinking obscure IPs in the IPV6 space are secure because "nobody could guess them so I don't need security" when in reality it's already an active attack vector due to the way clocks get adjusted leaking the IP. 3. It used to be that you couldn't just track someone forever because the IPs needed to get recycled. Now until I destroy a device there is a decent chance it can have the same IP for good, even if I run browsers in VMs with adblockers and scrambled browser fingerprints.
Obviously we all like a larger address space, but it's coming with some downsides.