It's certainly possible to do a lot better than GCC's inline assembly setup, which has proven time and again to be a usability disaster that positively encourages writing subtly buggy code.

Microsoft's C compilers do a much better job with inline asm by being more conservative in how they allocate registers around the asm (https://msdn.microsoft.com/en-us/library/k1a8ss06.aspx).

CodeWarrior's PPC compilers remain the ne plus ultra of inline assembly ergonomics, and it's a goddamn shame that LLVM has chosen (for pragmatic reasons) to follow GCC's mediocre lead rather than pursue something akin to it.