Thanks. I'm a big fan of her books, blog, and philosophy in general. I hope she doesn't lay low for too long, but she's given so much to the programming/online community that I guess she deserves a break if she wants one.
As somebody who devoured her twitter, I do feel an absence. But I do think she's working on similar stuff/themes at the moment, as she was pre-Twitter break.
I'd always been (stupidly) dismissive of Head First until I saw her speak at FOWA in 2008. Since then I've become incredibly impressed with her understanding of how people relate to computers.