I think what it comes down to more than anything is equality. What happens when someone discovers a breakthrough to reverse aging or to improve cognitive functioning? Should that information be public, or only accessible to the rich?
Now take the same analogy to computing. How many people have access to entire data centers to run algorithms for machine learning and AI? Doing your own computing is the opposite of that. Instead of sharing your information, it's saying we should build software and applications that run locally and that are open source so that we can audit the code. It's sad that the norm is everything in the cloud these days without any concern for privacy.