https://en.wikipedia.org/wiki/DO-178C#Software_level
The OMF system described in the video is Level E, meaning it's failure would have no safety impact on the aircraft. This gives us greater latitude in choice of software solutions. The higher levels, however, have strict requirements regarding latency and memory management that would automatically preclude the use of Clojure or any language with garbage collection.
So, as always, it's selecting the right tool for the job.
> At present, more than 98 system types have been certified using SCADE DO-178B/C certified tools, for more than 53 aircraft programs, by multiple certification authorities, worldwide, such as the FAA, EASA, Transport Canada, and ANAC, for Levels C to A.
http://www.esterel-technologies.com/industries/do-178b-and-d...