Do I need to care about any more configurations when using it along with proguard? Like extra lines in proguard.txt or change of mapping files when uploading to my crash reporting tools?
If you're using third-party crash reporting tools that don't understand that back-map, though, you can always turn off the source stripping. We describe how to do that here: https://github.com/facebook/redex/blob/master/docs/Config.md.