But...there are some exceptions!
There are certainly a handful of examples of responding to the last question you pose - re: being independent and achieving mainstream success. The ones that I find the most relevant are CHVRCHES (unsigned, SoundCloud got them attention, eventually had their pick of labels) and Macklemore (independent, used major label distribution services though). Also Skrillex - his label had no interest in his bleep-blonk-screech-BASS DROP tunes and he set it free online and got that avenue going - now he's got his own label and millions in the bank. There are some outlier musicians like Prince who are genuinely contentious with both industry and fan expectations.
I think more and more artists who grow up as 'one-person operations' (think Grimes) will navigate a new business platform. Labels will specialize in these artists, or management teams. Eventually though, there does exist a plateau where it seems inevitable to have to deal with a large entity such as LiveNation or Ticketmaster...neither of which are very well regarded as customer friendly in this day and age - at least not as much as direct-to-fan opportunities. The next 10 years should be interesting both in the US and globally.
Oh, and in my opinion, artists tend to start labels as a compensation mechanism to get more power for their own business enterprise, and potentially profit from the success of others signed (see: Cash Money / Young Money Records).