I have over the past seven years taken ayahuasca more times than anyone who isn't studying to become a shaman probably reasonably should. (Still debating the apprenticeship, but leaning strongly towards yes.) Doing so — and, more specifically, the changes I have witnessed and implemented consequent to those experiences — has, without question or hesitation, improved pretty much every aspect of my life. I'm smarter, I'm happier, I'm calmer, and I have a better and more diverse community of friends; I've shed bad habits, delusions, maladaptive behaviors, and people who brought — and kept — me down.
Many regard it as form of "cheating" your way towards enlightenment — as if that's even a thing. I think that's a misinformed and prejudiced attitude; and, yet, if you look at it in a non-judgemental light, it's also a little bit true. Psychedelics, taken intentionally, can be powerfully positively transformative, and they can get you there in an eyeblink.
Literally, I've had years-, even decades-old behavior patterns that were limiting me that evaporated instantly, never to return, after ceremonial experiences that showed me what was behind those patterns, why I kept engaging in them, and how that was holding me back. Others have taken a bit more chipping away at, but the end result is the same: a way of engaging with the world that wasn't conducive to success or happiness or whatever is recognized, and changed, and the experience you have of life, particularly in places where those patterns would previously have been expressed, is forever changed, for the better.
There are risks, and they most definitely aren't for everyone, but for those for whom they are indicated, and who are willing to engage with the experience as a transformative one, and not merely one of, "Ooh, pretty colors!" the only things that limit how far you can go are yourself, and the laws of physics — and I'm starting, sometimes, to question the latter (or, rather, some of the assumptions behind them) a bit...
EDITs: there were many.