I used to have ridiculous eye strain when staring at the computer screen for hours, but after getting a pair it's all but gone away. Like many here, I spend all day in front of a computer programming. Now I can't go anywhere I'll be using a computer for a prolonged period of time without them. When I bought them I thought they were a bit of a gimmick that worked mostly on the placebo effect, but after using them for close to a year, I can honestly say they have made a great impact on my ability to do work. I'd highly recommend that anyone who hasn't and has issues with eye strain give them a try.
Note, I do not work with Gunnar, nor am I associated with them in any way shape or form other than being a happy consumer.